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News Collection

February 27, 2017 

  Presynaptic Calmodulin targets: lessons from structural proteomics.

Lipstein, N.; Göth, M.; Piotrowski, C.; Pagel, K.; Sinz, A.; Jahn, O. Presynaptic Calmodulin targets: lessons from structural proteomics. Expert Review of Proteomics 2017; 14:223-242, doi: 10.1080/14789450.2017.1275966. Abstract. 


January 13, 2017 

  Partial immunoblotting of 2D-gels: A novel method to identify post-translationally modified proteins.

Kusch, K.; Uecker, M.; Liepold, T.; Möbius, W.; Hoffmann, C.; Neumann, H.; Werner, H. B.; Jahn, O. Partial immunoblotting of 2D-gels: A novel method to identify post-translationally modified proteins exemplified for the myelin acetylome. Proteomes 2017; 5:3. Abstract. 


May 12, 2016 

  Characterization of N-terminally elongated Aß variants.

Beyer, I.; Rezaei-Ghaleh, N.; Klafki, H.-W.; Jahn, O.; Haußmann, U.; Wiltfang, J.; Zweckstetter, M.; Knölker, H.-J. Solid-phase synthesis and characterization of N-terminally elongated Aβ−3–x-peptides. Chemistry - A European Journal 2016; 22:8685-93. Abstract. 


July 22, 2014 

  Development of 13C-labeled Bpa.

Pettelkau, J.; Ihling, C.H.; Frohberg, P.; van Werven, L.; Jahn, O.; Sinz A. Reliable Identification of Cross-Linked Products in Protein Interaction Studies by 13 C-Labeled p-Benzoylphenylalanine. Journal of The American Society for Mass Spectrometry 2014; 25:1628-41. Abstract. 


April 30, 2013 

  Innovations in automated 1D gel-based proteomics.

Schmidt, C.; Hesse, D.; Raabe, M.; Urlaub, H.; Jahn, O. An automated in-gel digestion / iTRAQ-labeling workflow for robust quantification of gel-separated proteins. Proteomics 2013; 13:1417-22. Abstract. 


November 05, 2012 

  Calmodulin-dependent regulation of priming activity is structurally and functionally conserved in all Munc13 proteins.

Lipstein N., Schaks S., Dimova K., Kalkhof S., Ihling C., Kölbel K., Ashery U., Rhee J., Brose N., Sinz A., Jahn O. Non-conserved Ca2+/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity. Molecular and Cellular Biology 2012; 32:4628-4641. Abstract. 


May 24, 2012 

  A new resource for the molecular dissection of CNS myelin biology.

de Monasterio-Schrader, P.; Jahn, O.; Tenzer, S.; Wichert, S.P.; Patzig, J.; Werner, H.B. Systematic approaches to central nervous system myelin. Cellular and Molecular Life Sciences 2012; 69:2879-94. Abstract. 


Please visit our myelin proteome web resource for further details. 

November 16, 2011 

  Photoaffinity labeling reveals structural insights into mitochondrial protein import.

Schulz, C.; Lytovchenko, O.; Melin, J.; Chacinska, A.; Guiard, B.; Neumann, P.; Ficner, R.; *Jahn, O.; Schmidt, B.; Rehling, P. Tim50’s presequence receptor domain is essential for signal driven transport across the TIM23 complex. Journal of Cell Biology 2011; 195:643-656 (*co-corresponding author). Abstract. 


November 10, 2011 

  First systematic analysis of the PNS myelin proteome.

Patzig, J.; *Jahn, O.; Tenzer, S.; Wichert, S.P.; de Monasterio-Schrader, P.; Rosfa, S.; Kuharev, J.; Yan, K.; Bormuth, I.; Bremer, J.; Aguzzi, A.; Orfaniotou, F.; Hesse, D.; Schwab, M.H.; Möbius, W.; Nave, K.-A.; Werner, H.B. Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci. Journal of Neuroscience 2011; 31:16369-16386 (*co-first author). Abstract. 


June 03, 2009

  First structural insights into the Calmodulin-Munc13 complex.

Dimova, K.; Kalkhof, S.; Pottratz, I.; Ihling, C.; Rodriguez-Castaneda, F.; Liepold, T.; Griesinger, C.; Brose, N.; Sinz, A.; Jahn, O. Structural insights into the Calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. Biochemistry 2009; 48:5908-5921. Abstract. 


December 04, 2007

  In-depth proteome analysis of Arabidopsis leaf peroxisomes.

Reumann, S.; Babujee, L.; Ma, C.; Wienkoop, S.; Siemsen, T.; Antonicelli, G.E.; Rasche, N.; Lüder, F.; Weckwerth, W.; Jahn, O. Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. Plant Cell 2007; 19:3170-3193. Abstract. 


July 19, 2007 

  News on the CNS myelin proteome.

Werner, H.B.; Kuhlmann, K.; Shen, S.; Uecker, M.; Schardt, A.; Dimova, K.; Orfaniotou, F.; Dhaunchak, A.; Brinkmann, B.G.; Möbius, W.; Guarente, L.; Casaccia-Bonnefil, P.; Jahn, O.; Nave, K.A. Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. Journal of Neuroscience 2007; 27(29):7717-7730. Abstract. 


August 22, 2006 

  Automation advances in gel-based proteomics.

Jahn, O.; Hesse, D.; Reinelt, M.; Kratzin, H. D. Technical innovations for the automated identification of gel-separated proteins by MALDI-TOF mass spectrometry. Analytical and Bioanalytical Chemistry 2006; 386:92-103. Abstract. 


June 05, 2019


Cells Special Issue "25 Years of Proteomics in Cell Biology".


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October 30, 2018


Proteomic phenotyping platform contributes to the identification of a signalling pathway regulating neuron polarity.


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April 16, 2018


SUMO and aging.


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